NDUFAF6 and Leigh syndrome: Favourable outcomes with NDUFAF6 deficiency were reported in a recent study by Baide‐Mairena et al.21 LS is genetically heterogeneous and is caused by defects in many different molecules involved in OXPHOS.22 Our observations highlight the importance of identifying the biochemical and genetic background of the disease in each case to discuss the mortality due to the disease.