WNT/β‐catenin signalling abnormal activated is one of the majority causes leading to various human cancers including colon cancer.19, 20 WNT signalling also induces EMT process and finally promotes tumour metastasis.21 As mentioned previously, CCAT2, located at 8.24.21, was proved to be involved in tumorigenicity through activating WNT/β‐catenin signalling. The gene discussed is CCAT2; the disease is malignant colon neoplasm.