It is reported that lncRNAs exert its function by diverse mechanisms depending on its cellular location.7, 8, 9, 10 The 8q24.21 locus harbours several cancer‐related lncRNAs and few protein‐coding genes.11 The MYC oncogene, located in this region, contributes to the tumorigenesis in many human cancers including colon cancer.12, 13 Previous reports demonstrated that lncRNAs mapped to 8q24.21 locus paly potential roles by directly or indirectly interacting with MYC. The gene discussed is MYC; the disease is cancer.