Survival analysis showed that higher expression of AC131571.1, ANO1‐AS2, ITCH‐IT1, ARHGEF26‐AS1, AP004609.1, LINC00491, KCNQ1OT1, MACROD2‐IT1, TSSC1‐IT1 or LINC00355 was correlated to poor OS in patients with colon cancer. The gene discussed is ARHGEF26; the disease is malignant colon neoplasm.