Survival analysis showed that higher expression of AC131571.1, ANO1‐AS2, ITCH‐IT1, ARHGEF26‐AS1, AP004609.1, LINC00491, KCNQ1OT1, MACROD2‐IT1, TSSC1‐IT1 or LINC00355 was correlated to poor OS in patients with colon cancer. This evidence concerns the gene LINC00491 and malignant colon neoplasm.