FER1L4 and nonpapillary renal cell carcinoma: Also, univariate (OS: HR 7.664, 95% CI 2.38–24.67, p = 0.001; CSS: HR 9.211, 95% CI 2.40–35.39, p = 0.001; PFS: HR 3.63, 95% CI 1.31–10.05, p = 0.013) and multivariate Cox regression analyses (OS: HR 7.06, 95% CI 1.88–26.44, p = 0.003; CSS: HR 10.686, 95% CI 2.21–51.61, p = 0.003, PFS: HR 3.56, 95% CI 1.19–10.62, p = 0.022) demonstrate an independent and significant value of Fer1L4 as prognostic biomarker in ccRCC patients (Tables 3, 4, 5), with higher expression meaning poor survival.