SSH1 and neoplasm: The univariate analysis model indicated that tumor size (HR = 1.566, p = 0.015), pathological grade (HR = 1.325, p = 0.024), lymphovascular invasion (HR = 1.838, p < 0.001), squamous differentiation (HR = 1.492, p = 0.032), tumor recurrence (HR = 3.451, p < 0.001), progression (HR = 2.947, p < 0.001), and SSH-1 positive expression (HR = 1.693, p < 0.001) showed prognostic implication for the predication of CCS in patients with bladder UC (Table 2).