The similarity between lupus models (without the experimental interventions) of FcGRIIb−/− mice and pristane induction was demonstrated by non-significant differences in survival analysis, serum creatinine (Cr) and proteinuria, although 6 out of 30 pristane mice developed ascites by visual observation as early as 6.2 ± 0.5 wk old (Fig. 2). The gene discussed is FCGR2B; the disease is systemic lupus erythematosus.