As the expression of TGFβ receptors (TGFBR1, 2 and 3) was upregulated in CAF-S1 cells compared to CAF-S4 (Supplementary Fig. 5h), we compared the impact of TGFBR inhibitor on CAF-S1- and CAF-S4-induced EMT initiation on cancer cells (Fig. 7c and Supplementary Fig. 5i). The gene discussed is TGFBR1; the disease is cancer.