In addition, Hung et al. recently demonstrated that fibrotic stimuli by administration of bleomycin induced lung fibrosis in mice in which Itga8 was genetically deleted on platelet-derived growth factor beta-positive stromal cells as well as in the control mice, suggesting that ITGA8 was not involved in the collagen production of the mouse lung fibrosis model [30]. This evidence concerns the gene ITGA8 and pulmonary fibrosis.