Whereas IL-27 levels were correlated with TCC in patients with falciparum malaria with and without HIV, but not in HIV-infected patients without malaria, IL-27 were correlated with IL-8 only in the latter group and notably, IL-27 levels were significantly correlated with IP-10 and sCD25 in all the three subgroups of patients (malaria only, malaria+HIV and HIV only) (Table 4). This evidence concerns the gene CXCL10 and Plasmodium falciparum malaria.