Whereas there were no association between IL-27 levels and cerebral malaria (Glascow Coma Score ≤ 11), renal dysfunction (serum creatinine > 265 μM) and pulmonary oedema, IL-27 levels were significantly higher in those with severe anemia (< 5 g/dl) as compared with those without this manifestation (Table 3). This evidence concerns the gene IL27 and Abnormal renal physiology.