Interestingly, plasma levels of IL-27 were positively correlated with vWF in patients with malaria alone and in HIV-infected patients without malaria (r = 0.54, p < 0.001), but not in those that were co-infected with HIV and malaria (Fig. 2b), potentially indicating some interactions between HIV and falciparum malaria that affects the pattern of endothelial cell activation. Here, IL27 is linked to Plasmodium falciparum malaria.