The authors demonstrated the inhibition of the expression of specific oncogenic microRNAs (miRs) such as miR-21, miR-19, and miR-30a-5p in glioma cells, which was consequently associated with altered expression of their targeting genes such as p53, STAT3, EGFR, COX-2, NF-κB, and the PI3K/AKT/mTOR signaling pathway. This evidence concerns the gene TP53 and central nervous system cancer.