DDIT3 and cancer: T3 induced ER stress in cancer cells, which is evidenced by the increased levels of ER stress-related proteins, such as binding immunoglobulin protein (BiP), eukaryotic Initiation Factor 2α (eIF2α), protein kinase R-like ER-localized eIF2α kinase (PERK), inositol-requiring enzyme 1α (IRE1α) and C/EBP homologous protein (CHOP) [371,374,377,385].