Nevertheless, in EBV-associated HL both cytotoxicity markers, CD8 and GrB, were increased compared to EBV+ GC, but this difference was not observed when CD8 and GrB cell counts were compared in EBV− HL and GC, suggesting a collaborative influence of EBV in the HRS tumor cells to recruit cytotoxic immune cells. Here, CD8A is linked to neoplasm.