STAT3 and acute myeloid leukemia: However, a dual-function molecule CpG-STAT3 dODN, which consists of a STAT3 dODN fused to the TLR9 agonist cytosine guanine dinucleotide (CpG), was reported to induce growth-inhibitory and immune-mediated effects against AML and DLBCL [74,344].