In recent years, a growing body of evidence has been provided assessing that other FA gene products, such as FANCA, FANCC, and FANCD2 are connected to mitochondrial function [111,112,113,114] such as energetic function, altogether providing a link between OS and MDF in FA as well as in a number of cancer-prone genetic diseases, as discussed by Perrone et al. [115]. The gene discussed is FANCA; the disease is cancer.