In particular, a direct role on platelets by Liraglutide, an analog of the incretin hormone glucagon-like peptide 1 (GLP-1), initially used for the treatment of T2DM and recently introduced as potential weight loss medication, cannot be excluded because Liraglutide has been shown to inhibit platelet activation in animal models [128] and human platelets [129]. Here, GCG is linked to type 2 diabetes mellitus.