ATM and familial pancreatic carcinoma: Inherited genetic factors are thought to underlie susceptibility in up to half of FPC families [5,6,7], with pathogenic germline variants in pancreatic cancer susceptibility genes, including ATM, BRCA1, BRCA2, CDKN2A, CPA1, CPB1, MLH1, MSH2, MSH6, PALB2, PMS2, PRSS1, and STK11, associated with a high risk of developing PDAC [8].