To assess the in vivo effect of SLMP53-1 on glucose metabolism, the expression levels of glycolytic and OXPHOS molecular markers were evaluated by immunohistochemistry (IHC) staining in tumor tissues of xenograft mouse models carrying p53+/+ and p53−/− HCT116 cells obtained in previous work [24] (Figure 2A,B). This evidence concerns the gene TP53 and neoplasm.