CD274 and alveolar soft part sarcoma: ASPS is characterized by the specific chromosomal translocation t(X;17)(p11.2;q25) and is a vascular-rich sarcoma [87], but the mechanism underlying its response to immune checkpoint inhibitors is unknown; PD-L1 expression, the TMB, and the MSI-high status do not explain the high response rate of ASPS patients to immune checkpoint inhibitors.