TP53 and malignant colon neoplasm: It inhibited the growth of the colon cancer cell lines SW620 (IC50: 29.0 μM), HCT116 (p53+/+) (IC50: 30.0 μM) and HCT116 (p53−/−) (IC50: 34.0 μM) but did not show toxicity in the normal colon CCD-112 CoN cells up to 40 μM [71].