CXCL8 and breast cancer: Additionally, direct treatments with EPA and CAP + EPA significantly reduced MCF-7 BC cell inflammation, as demonstrated by significantly lower IL-6 and IL-8 mRNA transcription levels, while direct treatments with CAP reduced only IL-6 mRNA levels after 48 h compared with control in MCF-7 cells (Figure 2D,E) (p < 0.05).