Direct treatments with EPA, CAP, or CAP + EPA did not alter most measured markers of cancer cell growth and inflammation in MDA-MB-231 cells, with the exception of IL-8, which was significantly reduced by EPA and CAP + EPA treatments for 48 h in MDA-MB-231 cells (p < 0.05) compared with control (CT), while CAP alone had no effect. Here, CXCL8 is linked to cancer.