Interestingly, transient transfection of ESRP1 in PANC-1 cells led to an increase in expression of proteins including α-enolase, which is a prognostic marker in patients with pancreatic cancer, and filamin-α, which interacts with many proteins related to cancer metastasis [13,14,15,16]. This evidence concerns the gene ESRP1 and familial pancreatic carcinoma.