GATA4 and coronary artery disorder: A large number of ClinVar reported variants in GATA4 are associated with various forms of CHD, including three of the variants we identified c.1037C > T (p.Ala346Val), c.1180C > A (p.Pro394Thr), and c.1220C > A (p.Pro407Gln), in association with Atrio ventricular septal defect (AVSD4; MIM# 614430) (Table 1).