ZFPM2 and diaphragmatic hernia: About half (5) of the ZFPM2 variants we identified have not been previously reported, while the other five variants have been reported in ClinVar in association with congenital heart defects (TOF; MIM# 187500), diaphragmatic hernia (DIH3; MIM# 610187), or 46, XY DSD (SRXY9; MIM# 616067).