TGFB1 and Hepatic fibrosis: Hepatic stellate cell activation plays a key role in the pathogenesis of liver fibrosis.17 It is known that TGF‐β1 triggers AMPK signal pathway activation in liver fibrosis and HSC activation.18 The implication of DNA methylation and LncRNAs in liver fibrosis has been increasingly discovered.19, 20 In this study, we have demonstrated LncRNA ANRIL, which is involved in the attenuation of HSC activation in liver fibrosis.