TCF7L1 and neoplasm: The aa 33‐410 region of Tcf7l1 is the binding domain between Tcf7l1 and JMJD6, which is also responsible for the interaction of Tcf7l1 with Groucho.79 Moreover, miR‐770 binds to the 3′UTR of JMJD6 mRNA and suppresses its expression, resulting in the downregulation of WNT/β‐catenin pathway, thereby exerting anti‐tumour effect.80