Since Wnt signalling is critical for the activity of epithelial stem cells, it is not surprising that Wnt signalling is frequently upregulated in cancer.77 In glioma stem cells, cignal finder cancer 10‐pathway reporter array was adopted to explore the signalling pathways involved in the association between JMJD6 and increased cell proliferation, migration and invasion.13 The results demonstrated that silencing of JMJD6 with JMJD6‐shRNA suppresses Wnt signalling and activates p53 signalling. The gene discussed is JMJD6; the disease is cancer.