MITF and melanoma: Jumonji domain‐containing protein 6 regulates melanogenesis in melanoma cells because overexpression of JMJD6 promotes the expression of microphthalmia‐associated transcription factor (MITF), a master regulator of melanogenesis.63 JMJD6 facilitates multiple cellular processes, including proliferation and invasion of melanoma cells in vitro, and promotes growth and metastasis of melanoma in vivo.63 At later stages of melanoma development in zebrafish, the expression of JMJD6 is elevated.64 Furthermore, JMJD6 is capable of enhancing blood vessel formation in melanoma.63