Inhibiting JMJD6 with short hairpin RNA (shRNA) or single‐guide RNA (sgRNA) could not alter cell growth, colony formation and survival in vitro.73 In the orthotopic xenograft mouse model, targeting JMJD6 is of great benefits to survival, and sustained JMJD6 inhibition may provide even better anti‐tumour effects.73 In addition, compared with mice implanted with normal glioblastoma cells, the survival of mice bearing JMJD6‐deficient glioblastoma cells is significant improved. This evidence concerns the gene JMJD6 and glioblastoma.