To further examine the relationship between NAFLD and plasma sE‐selectin levels, independent of potential confounders, we studied the association of two NAFLD susceptibility genes, that is, PNPLA3 (rs738409) and GCKR (rs1260326), with plasma sE‐selectin levels in the combined CODAM and Hoorn studies (n = 1265, see Table 1 for characteristics). The gene discussed is GCKR; the disease is metabolic dysfunction-associated steatotic liver disease.