Previous studies have shown that plasma ALT is not a perfect biomarker of NAFLD severity, although simple steatosis and NASH have been associated with greater plasma ALT levels.41, 42 It is therefore likely that there is a residual ‘NAFLD effect’ on sE‐selectin levels when plasma ALT is entered as an independent variable in the regression model. Here, GPT is linked to metabolic dysfunction-associated steatotic liver disease.