IDH1 and neoplasm: However, in patients with an IDH1R132H tumor, TERTp status did not significantly associate with survival (Fig. 2e), and multivariate analysis unveiled that TERTp status was not an independent prognostic factor when adjusting for age, WHO grade, and IDH1 status (HR 1.06; 95% CI 0.50–2.24; p = 0.87).