FOXD2 and cancer: Moreover, analysis results from Kaplan–Meier Plotter Pan-cancer RNA sequencing public webserver (http://kmplot.com/analysis/index.php?p=service&cancer=pancancer_rnaseq) indicated that higher level of FOXD2-AS1 was significantly associated with poorer OS in all head and neck cancer cases, and stage IV head and neck cancer cases (Fig. 1d–f).