Among these 48 DEGs, eight genes were identified in previous studies of schizophrenia or schizophrenia related pathways (Table 1): HGF, PRRT2, EGR1, EGR3, C11orf87, TLR3, PLEKHH2 and PIK3CD (Fisher exact test, P = 0.00021). The gene discussed is PLEKHH2; the disease is schizophrenia.