The effect of NUP93 silencing on AC remodeling appears not to be limited to this breast cancer subtype as we observed changes, although more modest, in luminal A MCF-7 (Fig S4), HER2+ MDA-361 (Fig S4), and triple-negative BT-20 (Fig S4) cell lines as well as in non–small cell lung cancer cells H1299 (Fig S5A and B). Here, ERBB2 is linked to breast cancer.