Extrapolating these findings to human cancer, we show that murine CD80+ SCC cells that are highly responsive to BI 853520 co-express a number of genes associated with a cancer stem phenotype that has previously been identified in human SCC tumors (Miao et al., 2019; Oshimori et al., 2015) and that a substantial proportion of human cancer cell lines representing a broad range of cancer types express the CD80 transcript, supporting the potential for patient stratification based on cancer cell CD80 expression. Here, CD80 is linked to cancer.