PTK2 and neoplasm: Using this same model system we first determined the anti-tumor efficacy of a different FAK kinase inhibitor, that is BI 853520 (Hirt et al., 2018), by monitoring tumor growth following injection of FAK-deficient cells (FAK-/-) or FAK-deficient cells that re-expressed wild-type FAK (FAK-wt) at comparable levels to endogenous.