CTLA4 and juvenile idiopathic arthritis: At the same time, in boys with JIA with the insufficient response to methotrexate the CTLA4 rs3087243*GA genotype and the CTLA4 rs3087243*A allele were significantly more common, and the CTLA4 rs3087243*GG genotype was significantly less common, than in those with the sufficient response (*GA: 53.49% vs. 24.00%, P = 0.023, pcor = 0.022, OR = 3.642, 95% CI 1.188–11.379; *A: 38.37% vs. 20.00%, P = 0.035, pcor = 0.036, OR = 2.491, 95% CI 1.128–5.553; *GG: 34.88% vs. 68.00%, P = 0.012, pcor = 0.013, OR = 0.252, 95% CI 0.094–0.733, respectively).