The ability of neuropilin‐ 1 (NRP1) to bind and augment the action of growth factors such as vascular endothelial growth factor (VEGF), transforming growth factor‐β1 (TGF‐β1), placental growth factor (PLGF), HGF (scatter factor) and Semaphorins 3A, 4F (Pellet‐Many, Frankel, Jia, & Zachary, 2008) are consistent with its emerging role as a tumor promoting receptor acting by a number of mechanisms. The gene discussed is PGF; the disease is neoplasm.