Epithelial to mesenchymal transition (EMT) is the highlight affecting changes in adhesion factors and related signalling pathways and promotes cell migration during tumour metastasis.41 In vitro model studies of tumour cell lines provide evidence that EMT occurs in the process of cancer invasion.42 The EMT can be triggered by different inducers, including a variety of growth factors, transforming growth factor‐β (TGF‐β), hepatocyte growth factor (HGF) and epidermal growth factor (EGF). This evidence concerns the gene TGFB1 and neoplasm.