PECAM1 and neoplasm: Although angiogenesis is a complex process, being regulated and modified by multiple factors, VEGF‐A is considered the key player.22 However, despite the significantly lower expression of the CD31 capillary marker in the tumour mass of animals treated with A platensis (Figure 2A), the VEGF‐A protein expression was surprisingly higher in tumour tissues, reaching borderline significance (by 48%, P = .056, Figure 2B).