EDN1 and neoplasm: Treatment of mice xenografted with human pancreatic cancer with A platensis led to an underexpression of endothelin 1, pentraxin 3 and acidic fibroblast growth factor and an overexpression of 3 angiogenic proteins in tumours, including VEGF‐A and AREG acting via VEGFR or EGFR (Table 1a).