ARG1 and neoplasm: M1 TAMs can help the host resist to the invasion of viral and microbial to fight against tumours,31 whereas M2 TAMs had pro‐tumoural functions which can promote tumour cell survival, proliferation and dissemination.32 The mRNA levels of M2 genes (MR and Arg‐1) were markedly elevated in the tumour tissues of HFD group, which was contrary to the expression of M1 gene (iNOS; Figure 4A).