SPAG5 and liver dysplastic nodule: For example, lncRNA‐Gm4419 silence alleviated NF‐κB/NLRP3 inflammasome‐regulated inflammation in DN.21 Knockdown of lncRNA plasmacytoma variant translocation 1 (PVT1) inhibited podocyte damage and apoptosis in through upregulating forkhead box A1 (FOXA1).22 LINC01619 regulated miR‐27a/FOXO1 to trigger oxidative stress and podocyte injury in DN.23 SPAG5‐AS1 was discovered by our study as a neighbour gene to SPAG5 through browsing UCSC, indicating that SPAG5 might be regulated by SPAG5‐AS1.