Corroborating data from the literature have long documented that p38 activation can be induced by endotoxins (Han et al., 1993) and there is ample evidence to implicate p38 in metastasis of several cancers, including lung, gastric and prostate cancers (del Barco Barrantes and Nebreda, 2012). The gene discussed is MAPK14; the disease is prostate cancer.