NOD1 and cancer: Furthermore, using intravital microscopy (IVM), which allows for visualization of living cancer cells migrating through blood vessels and adhering to them in a more physiologically relevant model of the early steps of hematogenous metastasis, we determine that NOD1 activation can increase adhesion of circulating HT29 and MC38 cells to hepatic sinusoids, an effect that is eliminated with ML130 addition.