Ze Zhang et al used WGCNA and found out 12 key genes in head and neck squamous cell carcinoma, which were TIMP2, MIR198, LAMA4, FAM198B, MIR4649, COL5A1, COL1A2, OLFML2B, MMP2, FBN1, ADAM12, and PDGFRB 18. The gene discussed is OLFML2B; the disease is head and neck squamous cell carcinoma.