Furthermore, several matricellular proteins that are associated with collagen deposition are known to be involved in hepatic fibrosis, including osteopontin (OPN),11, 12, 13 tenascin C,14 cysteine‐rich acidic secreted protein (SPARC),15, 16, 17 and periostin.18 The gene discussed is SPP1; the disease is Hepatic fibrosis.