USPs have specifically been reported to play roles in cancers such as prostate cancer (USP2a, USP7, USP10)39–41, ovarian cancer (USP15, USP36)42,43, glioblastoma (USP9X)44, and colorectal cancer (USP4, USP7)45,46. The gene discussed is USP4; the disease is Familial prostate cancer.