In this study, we found that lncRNA MIAT expression was down‐regulated after catechin treatment in myocardial tissue of MI/R rat and H/R‐induced myocardial cells, indicating lncRNA MIAT might be involved in the protective role of catechin against MI/R injury or H/R‐induced myocardial cell apoptosis. This evidence concerns the gene MIAT and myocardial infarction.