Currently, there is no evidence that anti-diabetic therapies with glucagon-like peptide 1 (GLP-1) agonists, sodium-glucose cotransporter-2 (SGLT2) inhibitors nor dipeptidyl peptidase-4 (DPP4) inhibitor affect the development of atrial fibrillation [28]. This evidence concerns the gene SLC5A2 and atrial fibrillation.