Missense variants in PRNP have been reported in patients with genetic prion disease. The c.628G>A (p.V210I) variant has been reported in many patients with prion disease (Bagyinszky, Giau, Youn, An, & Kim, 2018; Biljan et al.., 2011; Furukawa., Kitamoto, Hashiguchi, & Tateishi, 1996; Imbriani et al., 2016; Mouillet‐Richard et al., 1999; Nozaki et al., 2010; Pocchiari et al., 1993; Ripoll et al., 1993; Shyu, Hsu, Kao, & Tsao, 1996; Tajima, Satoh, Mito, & Kitamoto, 2014). Here, PRNP is linked to prion disease.