IGHE and anaphylaxis: Together our results show that the sensitized-mice with decreasing dose of venom developed: a) anaphylaxis with scores ranging from mild to severe, depending on challenge routes; b) produced anaphylactic IgG1 and IgE Abs; c) showed Natterins-specific IgG in the sera; d) recruited eosinophils and neutrophils to the lungs and to the skin later after decay of symptoms.