Modulation of innate immune responses by poly(I:C) led to an increased expression of RANTES (regulated upon activation normal T cell expressed and secreted, also called CCL5) and interferon gamma (IFN-γ), increased recruitment of natural killer (NK) cells, and higher microglial numbers and subsequently a more effective clearance of the pathogen at the local site of infection and in the systemic circulation. This evidence concerns the gene IFNG and infection.