STING1 and Glucose intolerance: Among the genes assigned to these terms are three that potentially link immune response and metabolic stress: TMEM173, a gene that activates type I interferon production and promotes glucose intolerance and tissue inflammation under metabolic stress induced by high fat diets [36]; and the two cathelicidins, CATHB1 and CATH3, antimicrobial peptides that kill bacteria by puncturing their cell membranes.