VAV1 and Alzheimer disease: MiR-330 overexpression in an AD mouse model inhibited the activation of MAPK pathway (Mitogen-Activated Protein Kinase) by binding the 3′ UTR (untranslated region) of VAV1 (Vav guanine nucleotide exchange factor 1), reducing mitochondrial dysfunction, oxidative stress, and Aβ plaque deposition [111].