EGFR and cancer: In particular, in MesomiR-1, the TargomiR is composed of the following three elements: (i) a synthetic double-stranded RNA molecule which mimics the tumor suppressor miR-16 [198]; (ii) bacterial vesicles for the delivery of the RNA molecule; and (iii) an anti-Epidermal Growth Factor Receptor (EGFR) antibody which recognizes the EGFR expressed on only cancer cells.