The dysregulation of different cellular pathways are involved in the development of this disease, such as the PI3K/Akt/mTOR pathway (Phospoinositide 3-Kinase/Serine-Threonine protein Kinase/mammalian Target Of Rapamycin), promoting uncontrolled cellular proliferation and tumor growth and leading to physical and metabolic exhaustion of the host until its death [127]. The gene discussed is AKT1; the disease is neoplasm.