SETDB1 and cancer: miR-7 inhibits SETDB1 expression and suppresses EMT and is involved in the generation of CSCs and dissemination of cancer via the inactivation of SETDB1-induced STAT3 signaling, which results in reduced c-Myc and Twist-1 levels due to the absence of STAT3 binding to the promoters of c-Myc and Twist-1 [215].