AMPK suppresses tumor survival through inhibition of mTOR by increasing the expression of p-TSC2, a tumor suppressor gene [139], and leads to the inactivation of AKT and lipopolysaccharide (LPS)-induced IL-6/JAK2/STAT3 signaling in triple-negative breast cancer (TNBC) [140]. The gene discussed is ENSG00000280371; the disease is neoplasm.