Seven out of the ten top hub nodes from both BioGRID and StringDB constructed networks of low-grade astrocytoma samples accord with each other, namely erb-b2 receptor tyrosine kinase 4 (HER4), annexin A1 (ANXA1), vascular endothelial growth factor A (VEGFA), cyclin E2 (CCNE2), interleukin 6 receptor (IL6R), transforming growth factor beta 2 (TGFB2), and CD86 molecule (CD86). Here, IL6R is linked to astrocytoma (excluding glioblastoma).