In the end, clinical and laboratory factors previously found to be predictive of Legionella pneumonia either were not significantly different in the two groups or they were not tested consistently (e.g., C-reactive protein, lactase dehydrogenase, Creatine phosphokinase (CPK) [3,4,5,6,7,8,9,10,11]. Here, PIK3C2A is linked to Legionnaires' disease.