INS and Hypoglycemia: While the specific pathophysiology of this syndrome remains unclear, carbohydrate intake results in rapid elevations of plasma glucose, insulin, and C-peptide levels, with subsequent development of hypoglycemia during the later postprandial period (Patti et al. 2005, Service et al. 2005, Meier et al. 2006, Goldfine et al. 2007).